1. to make someone angry, make an opponent of someone
Professional
Social
to antagonise someone
To antagonize someone means to anger, agitate or otherwise aggravate someone. You might antagonize someone to challenge them or to encourage them to lose their temper. Similar meaning expressions include ‘to rile up’ and ‘work up’. You can use this in social and professional contexts.
Tom is not capable of dealing with customer complaints in a professional manner. All he does is antagonize them further with his poor attitude.